And Isaac entreated the Lord for his wife Though God had promised to multiply his family, he prayed for it; for God's promises must not supersede, but encourage our prayers, and be improved as the ground of our faith. Though he had prayed for this mercy many years, and it was not granted, yet he did not leave off praying for it.
Related Commentaries of Genesis 25:21
Genesis 25:21
21 And Isaac intreated the LORD for his wife, because she was barren: and the LORD was intreated of him, and Rebekah his wife conceived.