Therefore is the anger of the Lord kindled This implies that, before the time of that final vengeance, concerning which the prophecy principally treats, God had afflicted, or, rather, would afflict and chastise this rebellious people, with the most grievous calamities: that those calamities should consume many, who, being slain in the wars, should be trod upon by their enemies, like the dung in the streets; most certain indications these of the divine justice and wrath, while they, unawakened by these chastisements, would not so much as attempt to appease the divine displeasure, but would provoke it still more by repeated crimes; till, at length, it should come upon them to the uttermost. Vitringa. And the hills did tremble A metaphorical and hyperbolical description of a grievous calamity, familiar to the prophets: see the margin. For all this, his anger is not turned away, &c. This is not the end, as you vainly imagine, but, if you repent not, only the beginning of your sorrows, and an earnest of further miseries.
Related Commentaries of Isaiah 5:25
Isaiah 5:25
25 Therefore is the anger of the LORD kindled against his people, and he hath stretched forth his hand against them, and hath smitten them: and the hills did tremble, and their carcases were torng in the midst of the streets. For all this his anger is not turned away, but his hand is stretched out still.