Send it not empty - See the marginal references. The pagan idea of appeasing the gods with gifts, and the scriptural idea of expressing penitence, allegiance, or love to God, by gifts and offerings to His glory and to the comfort of our fellow worshippers, coincide in the practical result.
Related Commentaries of 1 Samuel 6:3
1 Samuel 6:3
3 And they said, If ye send away the ark of the God of Israel, send it not empty; but in any wise return him a trespass offering: then ye shall be healed, and it shall be known to you why his hand is not removed from you.