But tidings out of the east and out of the north shall trouble him - Shall disturb him, or alarm him. That is, he will hear something from those quarters that will disarrange all his other plans, or that will summon him forth in his last and final expedition - on that expedition in which “he will come to his end” Daniel 11:45, or which will be the end of this series of historical events. The reference here is to the winding up of this series of transactions, and, according to the view taken on Daniel 11:40 (see the note at that place), it is not necessary to suppose that this would happen immediately after what is stated in Daniel 11:43, but it is rather to be regarded as a statement of what would occur in the end, or of the manner in which the person here referred to would finally come to an end, or in which these events would be closed. As a matter of fact, Antiochus, as will be seen in the notes at Daniel 11:45, was called forth in a warlike expedition by tidings or reports from Parthia and Armenia - regions lying to the east and the north, and it was in this expedition that he lost his life, and that this series of historical events was closed. Lengerke says, Antiochus assembled an army to take vengeance on the Jews, who, after the close of the unfortunate campaign in Egypt, rose up, under the Maccabees, against Antiochus, 1 Macc. 3:10, following Then the intelligence that the Parthians in the east, and the Armenians in the north, had armed themselves for war against him, alarmed him. So Tacitus (Hist. v. 8) says (Antiochus Judaeis), Demere superstitionem et mores Groecorum dare adnixus, quominus teterrimain gentem in melius mutaret, Parthorum bello prohibitus est, nam ea tempestate Arsaces defecerat. In the year 147 b.c., Antiochus went on the expedition to Persia and Armenia, on the return from which he died. The occasions for this were these:
(a) Artaxias, the king of Armenia, who was his vassal, had revolted from him, and
(b) he sought to replenish his exhausted treasury, that he might wage the war with Judas Maccabeus.
See 1 Macc. 3:27-37; Jos. Ant. b. xii. ch. vii. Section 2; Appian, Syriac. xlvi. 80; Porphyry, in Jerome, in loc.
Therefore he shall go forth with great fury to destroy ... - Great fury at the revolt of Artaxias, and especially at this juncture when he was waging war with the Jews; and great fury at the Jews, with a determination to obtain the means utterly to destroy them. 1 Macc. 3:27: “Now when king Antiochus heard these things (the successes of Judas Maceabeus), he was full of indignation.” In every way his wrath was kindled. He was enraged against the Jews on account of their success; he was enraged against Artaxias for revolting from him; he was enraged because his treasury was exhausted, and he had not the means of prosecuting the war. In this mood of mind he crossed the Euphrates (1 Macc. 3:37) to prosecute the war in the East, and, as it is said here, “utterly to make away many.” Everything conspired to kindle his fury, and in this state of mind, he went forth on his last expedition to the East. Nothing, in fact, could better describe the state of mind of Antiochus than the language used here by the angel to Daniel.