And they that are Christ’s - All who are true Christians.
Have crucified the flesh - The corrupt passions of the soul have been put to death; that is, destroyed. They are as though they were dead, and have no power over us; see the note at Galatians 2:20.
With the affections - Margin, “Passions.” All corrupt desires.
And lusts - See the note at Romans 1:24.