Thou knowest that I am not wicked - That is, that I am not a hypocrite, or an impenitent sinner. Job did not claim perfection (see the note at Job 9:20), but he maintained through all this argument that he was not a wicked man, in the sense in which his friends regarded him as such, and for the truth of this he could boldly appeal to God. The margin is, “It is upon thy knowledge.” This is a literal translation of the Hebrew, but the sense is well expressed in the text. The meaning of the verse is, “Why dost thou thus afflict me, when thou knowest that I am not wicked? Why am I treated as if I were the worst of men? Why is occasion thus furnished for my friends to construct an argument as if I were a man of singular depravity?”
There is none that can deliver out of thine hand - I have no power to release myself. Job felt hat God had almighty power; and he seems to have felt that his sufferings were rather the simple exertion of power, than the exercise of justice. It was this that laid the foundation for his complaint.