Upright men shall be astonished at this - At the course of events in regard to me. They will be amazed that God has suffered a holy man to be plunged into such calamities, and to be treated in this manner by his friends. The fact at which he supposes they would be so much astonished was, that the good were afflicted in this manner, and that no relief was furnished.
And the innocent shall stir up himself - Shall rouse himself, or assume vigor to resist the wicked.
The hypocrite - The wicked - alluding probably to his professed friends. The idea of hypocrisy which the sentence conveys arises from the fact, that they professed to be “his” friends, and had proved to be false; and that they had professed to be the friends of God, and yet had uttered sentiments inconsistent with any right views of him. He now says, that that could not go unnoticed. The world would be aroused at so remarkable a state of things, and a just public indignation would be the result.