He that loveth his life ... - This was a favorite principle, a sort of “axiom” with the Lord Jesus, which he applied to himself as well as to his followers. See the Matthew 10:39 note; Luke 9:24 note.
Related Commentaries of John 12:25
John 12:25
25 He that loveth his life shall lose it; and he that hateth his life in this world shall keep it unto life eternal.