Grievously sinned - literally, “Jerusalem hath sinned a sin,” giving the idea of a persistent continuance in wickedness.
Removed - Or, become an abomination. Sin has made Jerusalem an object of horror, and therefore she is cast away.
Yea, she sigheth ... - Jerusalem groans over the infamy of her deeds thus brought to open shame, and turns her back upon the spectators in order to hide herself.