The stones of the sanctuary - Or, the hallowed stones, literally stones of holiness, a metaphor for the people themselves. The actual stones of the temple would not be thus widely thrown about as to be seen everywhere, but the prophet has already affirmed this of the young children dying of hunger (compare Lamentations 2:19).
Related Commentaries of Lamentations 4:1
Lamentations 4:1
1 How is the gold become dim! how is the most fine gold changed! the stones of the sanctuary are poured out in the top of every street.