His holy prophets ... - All the prophets are said to have referred to the Messiah, from the beginning of the world. The most striking of these were Jacob Genesis 49:10; Moses Deuteronomy 18:15; Isaiah Isaiah 9:6-7; Isaiah 53:1-12.
Since the world began - This is not to be taken literally, for there were no prophets “immediately after” the creation. It is merely a general expression, designed to denote that all the prophets had predicted the coming of the Messiah. Compare the Luke 24:27 note; Revelation 19:10 note.