Deliver my soul, O Lord - My soul is harassed and distressed. Perhaps the meaning also may be, My life is in danger. Or, if it refers to the soul as such, then it means that everything pertaining to his soul was deeply affected by the course which was pursued. He was maligned, slandered, misrepresented, deceived, and he had no comfort or peace.
From lying lips - False, deceitful, slanderous. Compare the notes at Psalms 31:18.
And from a deceitful tongue - From a tongue whose statements cannot be relied on; whose words are deceptive; whose promises are false. David was often called to experience troubles of this sort; and this is a kind of trial which may come upon anyone in a form which he can no more anticipate or prevent than he can the coming of a “mist from the ocean.” No man can certainly guard against the influence of falsehood; no man can be sure that all that will be said to him is true; no man can be certain that all the promises made to him - save those made to him by God - will be performed.