Therefore is my spirit overwhelmed within me - See the notes at Psalms 77:3. Compare Psalms 42:5-7. His spirit was broken and crushed. He was in a state of despair as to any human help.
My heart within me is desolate - I have no comfort; no cheerfulness; no hope. My soul is like the waste desert where there is no water; where nothing grows; where there are only rocks and sands.