My heart panteth - The word rendered “panteth,” in its original form, means properly to go about; to travel around; and then, to travel around as a merchant or pedlar, or for purposes of traffic: Genesis 23:16; Genesis 37:28; Genesis 42:34. Applied to the heart, as it is here, it means to move about rapidly; to palpitate; to beat quick. It is an expression of pain and distress, indicated by a rapid beating of the heart.
My strength faileth me - It is rapidly failing. He regarded himself as rapidly approaching death.
As for the light of mine eyes - My vision; my sight.
It also is gone from me - Margin, as in Hebrew: “is not with me.” This is usually an indication of approaching death; and it would seem from all these symptoms that he appeared to be drawing near to the end of life. Compare Psalms 13:3; Psalms 6:7; Psalms 31:9.