They also that seek after my life - This was a new aggravation of his affliction, that those who were his enemies now sought to accomplish their purposes against him with better hopes of success, by taking advantage of his sickness.
Lay snares for me - On the meaning of this phrase, see the notes at Psalms 9:15. The idea here is that they sought this opportunity of ensnaring or entrapping him so as to ruin him. They took advantage of the fact that he was weak and helpless, and of the fact that he was forsaken or abandoned by his friends, to accomplish his ruin. how this was done is not stated. It might have been by their coming on him when he was thus helpless; or it might have been by endeavoring in his weak condition to extort confessions or promises from him that might be turned to his ruin. An enemy may hope to succeed much better when the one opposed is sick than when he is well, and may take advantage of his weak state of body and mind, and of the fact that he seems to be forsaken by all, to accomplish what could not be done if he were in the enjoyment of health, or sustained by powerful friends, or by a public opinion in his favor.
And they that seek my hurt - They who seek to injure me.
Speak mischievous things - Slanderous words. They charge on me things that are false, and that tend to injure me. The very fact that he was thus afflicted, they might urge (in accordance with a prevailing belief, and with the conviction of the psalmist also, Psalms 38:3-5) as a proof of guilt. This was done by the three friends of Job; and the enemies of the psalmist may thus have taken advantage of his sickness to circulate false reports about him which he could not then well meet.
And imagine deceits - Imagine or feign deceitful things; things which they know to be false or unfounded.
All the day long - Constantly. They seem to have no other employment. See Psalms 35:20.