Let not them that wait on thee - Those who worship thee; those who are thy true friends. True piety is often, in the Scriptures, represented as waiting on the Lord. See Psalms 25:3, Psalms 25:5; Psalms 37:9; Isaiah 40:31.
Be ashamed for my sake - On account of me; or, in consequence of what I do. Let me not be suffered to do anything that would make them ashamed of me, or ashamed to have it known that I belong to their number. I know that I am a sinner; I know that judgments come justly on me; I know that if left to myself I shall fall into sin, and shall dishonor religion; and I pray, therefore, that I may be kept from acting out the depravity of my heart, and bringing dishonor on the cause that I profess to love. No one who knows the evil of his own heart can fail to see the propriety of this prayer; no one who remembers how often people high in the church, and zealous in their professed piety, fall into sin, and disgrace their profession, can help feeling that what has happened to others “may” happen to him also, and that he has need of special prayer, and special grace, that he may go down into the grave at last without having brought dishonor upon religion.
Let not those that seek thee - Another phrase to denote people of true piety - as those who are “seeking” after God; that is, who are desirous of understanding his character, and obtaining his favor.
Be confounded for my sake - Let them not feel “disgraced” in me; let them not feel it a dishonor to have it said that I am one of their number, or that I profess to be united to them.