Thou turnest man to destruction - In contradistinction from his own unchangeableness and eternity. Man passes away; God continues ever the same. The word rendered “destruction” - דכא dakkâ' - means properly anything beaten or broken small or very fine, and hence, “dust.” The idea here is, that God causes man to return to dust; that is, the elements which compose the body return to their original condition, or seem to mingle with the earth. Genesis 3:19 : “dust thou art, and unto dust shalt thou return.” The word “man” here, of course, refers to man in general - all people. It is the great law of our being. Individual man, classes of people, generations of people, races of people, pass away; but God remains the same. The Septuagint and the Latin Vulgate render this, “Thou turnest man to “humiliation;” which, though not the sense of the original, is a true idea, for there is nothing more humiliating than that a human body, once so beautiful, should turn back to dust; nothing more humbling than the grave.
And sayest, Return, ye children of men - Return to your dust; go back to the earth from which you came. Return, all of you without exception; - kings, princes, nobles, warriors, conquerors; mighty people, captains, and counselors; ye learned and great, ye honored and flattered, ye beautiful and happy, ye youthful and vigorous, and ye aged and venerable; whatever is your rank, whatever are your possessions, whatever are your honors, whatever you have to make you lovely, to charm, to please, to be admired; or whatever there is to make you loathsome and detestable; ye vicious, ye profane, low, grovelling, sensual, debased; go all of you alike to “dust!’ Oh, how affecting the thought that this is the lot of man; how much should it do to abase the pride of the race; how much should it do to make any man sober and humble, that he himself is soon to turn back to dust - unhonored, undistinguished, and undistinguishable dust!