A thousand shall fall at thy side - Though a thousand should fall at thy side, or close to thee. This alludes to the manner in which the pestilence often moves among people.
And ten thousand at thy right hand - Compare Psalms 3:6. The word “myriad” would better represent the exact idea in the original, as the Hebrew word is different from that which is translated “a thousand.” It is put here for any large number. No matter how many fall around thee, on the right hand and the left, you will have nothing to fear.
But it shall not come nigh thee - You will be safe. You may feel assured of the divine protection. Your mind may be calm through a sense of such guardianship, and your very calmness will conduce to your safety. This refers, as remarked above, to a “general” law in regard to the judgments of God. It is true that others, beside the dissipated, vicious, and debased, may be the victims; but the great law is that temperance, soberness, virtue, cleanliness, and that regard to comfort and health to which religion and virtue prompt, constitute a marked security - so marked as to illustrate the “general” law referred to in the psalm before us.