Acts 13:49 - Ellicott's Commentary On The Whole Bible

Throughout all the region. — This clearly involves a considerable period of active working. It was not in Antioch only, but in the “region” round about, the border district of the three provinces of Phrygia, Lycaonia, and Galatia, that the new faith was planted. Each town and village in that region presented the spectacle of at least some few men and women who no longer sacrificed to their country’s gods, who were no longer content even to worship in the synagogue of the relligio licita of the Jews, but met in small companies here and there, as the disciples of a new Master.