The margin is more correct, and gives the key to the passage. Render, and offer by burning your thank-offering of leaven. Leaven was not allowed in any sacrifice offered by fire. Amos ironically calls upon them to break the Levitical law (Leviticus 7:13; Leviticus 23:17), as he knew they were in the habit of doing.
Related Commentaries of Amos 4:5
Amos 4:5
5 And offerc a sacrifice of thanksgiving with leaven, and proclaim and publish the free offerings: for this liketh you, O ye children of Israel, saith the Lord GOD.