A running issue out of his flesh. — Flesh, as is frequently the case, euphemistically denotes private parts. (See Genesis 6:10; Genesis 7:13; Leviticus 6:3; Leviticus 16:4; Ezekiel 16:26; Ezekiel 23:20, &c.)
Because of his issue he is unclean. — Better, his issue is unclean. Hence, any one coming in contact with it, or with the garment on which traces of the secretion are found, is thereby rendered unclean.