What have we to do with thee? — The cry is identical with that of the Gadarene demoniacs (Matthew 8:29). Here, as there, the possessed man has a preternatural intuition of our Lord’s greatness.
The Holy One of God. — The name occurs, as applied to Christ, only here, in the parallel passage of Luke 4:34, and in the better MSS. of John 6:69. It probably had its origin in the Messianic application of “Thy Holy One” in Psalms 16:10. Its strict meaning is “the Holy One whom God owns as such,” who has attained, i.e., the highest form of holiness.