The eyes of the Lord preserve knowledge — i.e., men who know and speak the truth. (See above on Proverbs 21:28.)
He overthroweth the words of the transgressor — i.e., the deceitful; He brings his lies to light.
Related Commentaries of Proverbs 22:12
Proverbs 22:12
12 The eyes of the LORD preserve knowledge, and he overthroweth the wordse of the transgressor.