My times are in thy hand — i.e., the vicissitudes of human life (LXX. and Vulg. have “my destinies”) are under Divine control, so that the machinations of the foe cannot prevail against one whom God intends to deliver. For the expression comp. 1 Chronicles 29:30, “the times that went over him,” Isaiah 33:6.
The sense of security in this trusting phrase may be contrasted with the feeling of danger in another Hebrew phrase, “my soul is continually in my hand,” Psalms 119:109.