Destroy. — Literally, make or count guilty.
Transgressions. — Literally, revolts, thus being in close synonymous parallelism with the next clause. Or else, as in margin and in ancient versions, LXX., Vulg., and Syriac, “Let them fall from their counsels:” i.e., “let their plots fail.”
On the imprecations in the Psalms see General Introduction, 6.