2 Corinthians 5:16 - Matthew Poole's English Annotations on the Holy Bible

Wherefore henceforth know we no man after the flesh: words of sense in Scripture ordinarily signify more than the act of that sense which they express; particularly this term know ordinarily signifieth to approve and acknowledge; and so it signifies here. We know, that is, we regard, we acknowledge no man in the discharge of our office; we regard no man with respect to any external fleshly consideration. Under which notion he comprehends all things not spiritual, whether carnal relations, riches, &c. Yea, though we have known Christ after the flesh; not from any sight of him, for we read not that Paul at any time saw Christ, but, Acts 9:1-43, when he saw him, not according to the flesh, but as exalted at the right hand of God: but by the hearing of the ear Paul had known Christ, as one that had lived in the flesh, and who had conversed with men for above thirty years; yet (saith he) we know him no more, we shall neither see nor hear him any more in the flesh; we now only know him as he hath a glorious body, with which he sitteth at the right hand of God.