2 Timothy 1:15 - Matthew Poole's English Annotations on the Holy Bible

This thou knowest: probably as to some he had a personal knowledge of their apostacy, as to others he knew it by information, which Paul confirmeth. That all they which are in Asia be turned away from me: it seemeth unreasonable to interpret all here of every individual, but many, as all oft signifieth in holy writ. Some interpret it of all the Jewish proselytes; others, of those of Asia who accompanied Paul to Rome, and there, seeing his sufferings, apostatized; others, of many who still abode in Asia, where Timothy now was: these all, or many of them, deserted Paul, either wholly casting off the Christian profession, or withdrawing themselves from communion with Paul, when they saw him a prisoner. Of whom are Phygellus and Hermogenes; of these two we have no more said in holy writ, and therefore can assert nothing of them with any certainty.