And be renewed; viz. more and more, being already renewed in part. In the spirit of your mind; i.e. in your mind which is a spirit: see 1 Thessalonians 5:23 2 Timothy 4:22. He means the superior powers of the soul, where regeneration begins, and which the philosophers magnified so much, and thought so pure.
Related Commentaries of Ephesians 4:23
Ephesians 4:23
23 And be renewed in the spirit of your mind;