Of treading down; in which my people are trodden under foot by their insolent enemies. Of perplexity by the Lord God of hosts: this is added, partly to show that this did not happen without God's providence; and partly to aggravate their calamity, because not only men, but God himself, fought against them. Breaking down the walls of the strong cities of Judah; which was done by Sennacherib, 2 Kings 25:10. Crying to the mountains, with such loud and dismal outcries as should reach to the neighbouring mountains, and make them ring again therewith.
Related Commentaries of Isaiah 22:5
Isaiah 22:5
5 For it is a day of trouble, and of treading down, and of perplexity by the Lord GOD of hosts in the valley of vision, breaking down the walls, and of crying to the mountains.