The curse; the curse of God threatened to transgressors, Deuteronomy 28:15, Deuteronomy 29:20, and imprecated by and upon themselves, if they should not persist in their obedience to God, Deuteronomy 27:26, and elsewhere. Are burned; are consumed by the wrath of God, which is commonly compared to fire.
Related Commentaries of Isaiah 24:6
Isaiah 24:6
6 Therefore hath the curse devoured the earth, and they that dwell therein are desolate: therefore the inhabitants of the earth are burned, and few men left.