Shall be ashamed and confounded, both because their hopes and designs shall be utterly disappointed, and because the mischief which they contrived against thee shall fall upon themselves. Shall be as nothing; shall come to nothing, or perish, as the next clause explains it.
Related Commentaries of Isaiah 41:11
Isaiah 41:11
11 Behold, all they that were incensed against thee shall be ashamed and confounded: they shall be as nothing; and they that strived with thee shall perish.