Isaiah 59:3 - Matthew Poole's English Annotations on the Holy Bible

Your hands are defiled with blood: here the prophet comes from a more general to a more particular charge against them; by blood we are to understand either murders and bloodshed properly so called; or ways of injustice, extortion, oppression, and cruelties, whereby men are deprived of a livelihood; hence hating our brother is called murder, 1 John 3:15, and the inhabitants of Jerusalem called murderers. See how the prophet phraseth their oppression, Micah 3:1-3. Your fingers: this is not added to protract the discourse, but to aggravate their sin: q.d. Not only your hands, but your fingers; you are not free from the least part of injustice. Your lips have spoken lies; not only properly so called, but perjuries, and wronging your neighbours by slanders and false accusations; wherein he shows they did not only offer violence by the hand, but they had ways of circumventing with their lips. Your tongue hath muttered: the verb doth properly signify to muse, or meditate; then the meaning is, that what they mutter, or utter with the tongue, they do it out of premeditated malice, from a perverse spirit; you may have a larger comment upon this Jeremiah 9:3-6. Perverseness: perverse words are such as are contrary to God's word, and it is put here in the abstract, to intimate that their words were every way contrary to God's will.