These words are an exhortation to the Jews to be willing, upon the first proclamation of liberty by Cyrus, to go out of Babylon, notwithstanding the pleasantness of the place, and that now their stakes had been pitched there many years, because of the ruin which should most certainly come on that place.
Related Commentaries of Jeremiah 51:45
Jeremiah 51:45
45 My people, go ye out of the midst of her, and deliver ye every man his soul from the fierce anger of the LORD.