Fail; or be consumed; either with grief and fears for their sore calamities; or with long looking for what they shall never attain, as this phrase is taken, Psalms 69:3 Jeremiah 14:6 Lamentations 4:17. And this shall be thy condition, O Job, if thou persistest in thine impiety. They shall not escape; they shall never obtain deliverance out of their distresses, but shall perish in them. As the giving up of the ghost, i.e. shall be as vain and desperate as the hope of life is in a man, when he is at the very point of death. Or, as a puff of breath, which is gone in a moment without all hopes of recovery.
Related Commentaries of Job 11:20
Job 11:20
20 But the eyes of the wicked shall fail, and they shall not escape, and their hope shall be as the giving up of the ghost.