But; or, surely, as this Hebrew particle most commonly signifies. He, i.e. God, as appears by the following words and verses. Hath made me weary; either of complaining, or of my life. Thou; he speaks in the second person to God, as in the former clause in the third person of God. Such change of persons are very usual in Scripture, and elsewhere. Hast made desolate all my company; hast turned my society into desolation, by destroying my children and servants.
Related Commentaries of Job 16:7
Job 16:7
7 But now he hath made me weary: thou hast made desolate all my company.