He seems to himself and others to be lost, and past all hopes of recovery; which he adds for Job's comfort in his desperate condition. To the destroyers; to the instruments of death or destruction, whether it be angels, whom God sometimes useth in those cases; or devils, who have the power of death. Hebrews 2:14; or diseases, which by God's appointment are ready to give the fatal blow.
Related Commentaries of Job 33:22
Job 33:22
22 Yea, his soul draweth near unto the grave, and his life to the destroyers.