John 16:2 - Matthew Poole's English Annotations on the Holy Bible

The term synagogue, as it is used often in Scripture to signify those places of public worship which they had in country towns and cities, is proper to the Jews; but as it signifieth an assembly of people met together in any place, it as well agreeth to other people as to them. Our Lord here, in pursuit of the argument which he hath been upon from 1 Thessalonians 15:18, forewarns his disciples, that when he should be taken from them, the Jews first should excommunicate them as heretics, or schismatics: and I know not why what our Saviour here saith may not also be extended as a prophecy of what hath since been done, and is yet doing, under the tyranny of the pope. As also the latter clause, which, though at first applicable to the Jews, who stoned Stephen upon a charge of blasphemy, in which it is apparent that they thought they did God good service, and doubtless slew many others; yet certainly it also referred to others, even as many as shall do the same thing to the end of the world.