Touch not; hurt not, as this word is used of these very persons, Genesis 26:11,29, and elsewhere. Mine anointed; my prophets, as the next words explain it, to wit, Abraham, and Isaac, and Jacob, as is evident; who are called God's anointed, because they were eminently blessed of God, and consecrated to be his peculiar people, and to be kings and priests in their families, and replenished with the gifts and graces of the Holy Ghost, in respect whereof many persons are said to be anointed in Scripture who never had any material oil applied to them, as Psalms 45:7 Isaiah 61:1 2 Corinthians 1:21. And they are called prophets, because God did familiarly converse with them, and revealed his mind and will to them, and by them to others; and because they were instructors or teachers of others in the true religion. See Genesis 18:19, Genesis 20:7.
Related Commentaries of Psalms 105:15
Psalms 105:15
15 Saying, Touch not mine anointed, and do my prophets no harm.