Then; in the midst of all their plots and confidences of success. Shall he speak to them in his wrath; he shall severely rebuke them, not so much verbally as really, by dreadful judgments. For God's speaking is oft put for his actions; and so here it is explained by vexing in the next branch. Or, he shall pronounce a terrible sentence against them.
Related Commentaries of Psalms 2:5
Psalms 2:5
5 Then shall he speak unto them in his wrath, and vexb them in his sore displeasure.