Psalms 6:4 - Matthew Poole's English Annotations on the Holy Bible

Return unto me, from whom thou hast withdrawn thyself, and thy smiling countenance, and thy helping hand. Deliver my soul, i.e. save me or my life, as the soul oft signifies, as Genesis 9:5, Genesis 12:5 Job 36:4 Psalms 33:19. David and other good men in those times were much afraid of death, partly because the manifestations of God's grace to his people were then more dark and doubtful, and partly because thereby they were deprived of all opportunities of advancing God's glory and kingdom in the world. Compare Isaiah 38:1-3.