As smoke is driven away— i.e. "As smoke is violently scattered and dispersed by the wind, so do thou shake and entirely disperse them with a force that they cannot resist." See Schultens in Proverbs 21:6.
Related Commentaries of Psalms 68:2
Psalms 68:2
2 As smoke is driven away, so drive them away: as wax melteth before the fire, so let the wicked perish at the presence of God.