For the zeal of thine house— That is, "My concern for thy holy worship has drawn a confederacy of irreligious men upon me, who are now just upon the point of compassing my ruin." But this verse had a more eminent completion in our Redeemer. See John 2:17 and Romans 15:3.
Related Commentaries of Psalms 69:9
Psalms 69:9
9 For the zeal of thine house hath eaten me up; and the reproaches of them that reproached thee are fallen upon me.