For in the hand of the Lord there is a cup, and the wine is red— And the wine is in a ferment. Hiller, 328. Is unmixed: Green; who renders the next clause, He filleth it up to the brim, and poureth out of the same. It is not improbable, that the wine here mentioned may allude to the stupifying and intoxicating liquor, which was given to criminals before their execution, either to hasten their death, or to lessen their sense of the pains they were to suffer; for it was a mixture of poisonous and stupifying herbs infused in wine. See Matthew 27:34.; Psalms 60:3. If we suppose some such intoxicating wine to have been in use at the time this psalm was written, it will account for the mixture here spoken of; a circumstance otherwise difficult to explain.
Related Commentaries of Psalms 75:8
Psalms 75:8
8 For in the hand of the LORD there is a cup, and the wine is red; it is full of mixture; and he poureth out of the same: but the dregs thereof, all the wicked of the earth shall wring them out, and drink them.