The first city — Neapolis was the first city they came to in that part of Macedonia which was nearest to Asia: in that part which was farthest from it, Philippi. The river Strymon ran between them. Philippi was a Roman colony.
Related Commentaries of Acts 16:12
Acts 16:12
12 And from thence to Philippi, which is the chiefa city of that part of Macedonia, and a colony: and we were in that city abiding certain days.