Behold to me thou hast given no seed — Not only no son, but no seed. If he had had a daughter, from her the promised Messias might have come, who was to be the Seed of the Woman; but he had neither son nor daughter.
Related Commentaries of Genesis 15:3
Genesis 15:3
3 And Abram said, Behold, to me thou hast given no seed: and, lo, one born in my house is mine heir.