Shut thy doors — Withdraw thyself from the world, and pour out thy prayers to God in thy closet. Indignation — The dreadful effects of God's anger, mentioned in the following verse.
Related Commentaries of Isaiah 26:20
Isaiah 26:20
20 Come, my people, enter thou into thy chambers, and shut thy doors about thee: hide thyself as it were for a little moment, until the indignation be overpast.