Let them that are in the midst of it — Where Jerusalem stands (that is, they that are in Jerusalem) depart out of it, before their retreat is cut off by the uniting of the forces near the city, and let not them that are in the adjacent countries by any means enter into it.
Related Commentaries of Luke 21:21
Luke 21:21
21 Then let them which are in Judaea flee to the mountains; and let them which are in the midst of it depart out; and let not them that are in the countries enter thereinto.