Therefore] in the sense of 'well then.'
First of all] His first exhortation as to Christian men is that they should pray. Supplications, prayers, intercessions, thanksgivings] The duty of the Christian Church in the matter of intercession is to offer prayers for others, and to give thanks for good things happening to others, and for events relating to others which may be a blessing to herself.
For all men] Christian charity and good-will excludes none.