Our heart with our hands] strictly, our heart to our palms, in the sense that the heart should actually follow in the direction in which our hands point (Jeremiah 4:31).
43-45 Zion's condition is dire because Jehovah will not hear the prayers of His miserable victims. People] RV 'peoples,' i.e. the foreign nations round about.
52-54. These vv. are thought to point to Jeremiah as the author of the poems: cp. Jeremiah 38. Cast a stone upon me] i.e. covered with a stone the pit into which they cast him. Waters flowed over mine head] There was no water, but mire, in Jeremiah's dungeon (Jeremiah 38:6). I am cut off] the sufferer is a type of Christ (Psalms 88:5; Isaiah 53:8).
55-66. In despair Zion prays for vengeance upon the enemy.