And it shall come to pass, that whosoever will not hearken unto my words,.... To the doctrines of the Gospel, but slight and despise them:
which he shall speak in my name; in whose name he came, and whose words or doctrines he declared them to be; not as his own, but his Father's, John 5:43.
I will require it of him; or, as the Targums of Onkelos and Jonathan,
"my Word shall require it of him, or take vengeance on him;''
as Christ the Word of God did in the destruction of the Jewish nation, city, and temple; see Luke 19:27.